8:30 am – 10:30 am

Session 1: Eosinophils and the Epithelium

8:30 am – 8:50 am

State-of-the-Art: Signaling Pathways that Regulate Eosinophilic Responses in the Mucosa 

Simon Hogan, United States 

8:51 am – 9:11 am 

Cutting-Edge: Homeostatic Roles of Intestinal Eosinophils 

Nicola L. Harris, New Zealand  

9:12 am – 9:32 am 

Cutting-Edge: Localized Immune Circuits to Regulate Eosinophils in the Skin Epithelium Barrier 

Sang Hun Lee, United States  

9:33 am – 9:48 am 

Oral Abstract 

9:49 am – 10:04 am 

Oral Abstract 

10:05 am – 10:20 am 

Oral Abstract 

10:21 am – 10:26 am 

Abstract Slam 

10:27 am – 10:32 am 

Abstract Slam 

10:30 am – 11:15 am

Coffee Break & Poster Viewing

11:15 am – 12:00 pm

Paul Ehrlich Award Lecture

Evolving Paradigms in Eosinophil Biology and Function – A Career's Journey: “There and Back Again” 

Steven Ackerman, United States  

Designed for Early Career Attendees, these sessions offer a unique opportunity to connect with experienced mentors over lunch. Complimentary lunch boxes will be provided.

Non-Academic Career Paths – Industry, Government, Editorial     

Andrew Menzies-Gow, United Kingdom

Calman Prussin, United States

Academic Career Paths – Clinical/Translational 

Praveen Akuthota, United States

Jean-Emmanuel Kahn, France

Princess Ogbogu, United States

Academic Career Paths - Basic 

Pedro Gazzinelli Guimaraes, United States

David Voehringer, Germany

2:00 pm – 3:30 pm

Session 2: Genetic Determinants in Eosinophilic Disease

2:00 pm – 2:05 pm 

Moderator Introduction

2:06 pm – 2:26 pm 

State-of-the-Art: Relationship between Genetic Variants that Regulate Blood Eosinophilia and Allergic Disease Risk

Leah Kottyan, United States 

2:27 pm – 2:47 pm 

Cutting-Edge: LNK (SH2B3) Deficiency and Eosinophilia and Arterial Thrombosis 

Nan Wang, United States  

2:48 pm – 3:03 pm

Oral Abstract 

3:04 pm – 3:19 pm

Oral Abstract 

3:20 pm – 3:25 pm

Abstract Slam 

3:26 pm – 3:31 pm

Abstract Slam 

4:00 pm – 5:30 pm

Session 3: New Roles of Eosinophils as Effector Cells

4:00 pm – 4:20 pm 

State-of-the-Art 

Leo Koenderman, Netherlands   

4:21 pm – 4:41 pm 

Cutting-Edge: Eosinophils Limit the Spread of Metastatic Pancreatic Cancer 

Stephanie K. Dougan, United States

4:42 pm – 4:57 pm

Oral Abstract 

4:58 pm – 5:13 pm

Oral Abstract 

5:14 pm – 5:19 pm

Abstract Slam 

5:20 pm – 5:25 pm

Abstract Slam 

5:30 pm – 7:30 pm

Poster Session Reception

Food and drink provided

8:00 pm – 10:00 pm

Early Career Networking Event

8:30 am – 10:45 am

Session 4: Eosinophils in Intestinal Immunity and Disease – Joint Session with CEGIR

8:30 am – 8:40 am  

Introduction

Marc Rothenberg, United States  

8:41 am – 9:26 am

Eosinophilic Disease Translational Research Award Lecture: Tissue Remodeling - Who is Responsible and What Does it Mean? 

Seema Aceves, United States  

9:27 am – 9:47 am

Cutting-Edge: Neuronal Regulation of Eosinophils in the Small Intestine 

Heping Xu, China  

9:48 am – 10:08 am

Cutting-Edge: Cellular and Molecular Mechanisms of Eosinophilic Esophagitis: Lessons from Experimental Models

Ariel Munitz, Israel

10:09 am – 10:24 am 

Oral Abstract  

10:25 am – 10:40 am 

Oral Abstract 

10:41 am – 10:46 am

Abstract Slam 

11:00 am – 1:00 pm

Poster Session

Lunch provided

1:00 pm – 3:00 pm  

Session 5: Mechanisms of Eosinophil Development, Heterogeneity and Plasticity 

1:00 pm – 1:20 pm 

State-of-the-Art: Regulation of the Eosinophil Lineage in Eosinophil-associated Diseases in the Context of Precision Therapy

Christophe Desmet, Belgium

1:21 pm – 1:41 pm 

Cutting-Edge: Transcriptional and Epigenetic Regulation of Eosinophil Development, Maturation and Tissue Specificity: Promoters, Enhancers and Beyond 

Jennifer Felton, United States    

1:42 pm – 2:02 pm 

Cutting-Edge: Transcriptional Regulation of Eosinophilopoiesis in Zebrafish 

Yiyue Zhang, China  

2:03 pm – 2:18 pm

Oral Abstract 

2:19 pm – 2:34 pm

Oral Abstract 

2:35 pm – 2:50 pm

Oral Abstract 

2:51 pm – 2:56 pm

Abstract Slam 

3:15 pm – 4:00 pm

Lifetime Achievement Award Lecture

Eosinophil Biology and Eosinophilic Disease

Dagmar Simon, Switzerland  

Hans-Uwe Simon, Switzerland  

4:00 pm – 4:30 pm

IES Business Meeting

IES Members Only

5:00 pm – 9:00 pm

Optional Networking Event

8:30 am – 10:30 am

Session 6: Eosinophils and Immunomodulation

8:30 am – 8:50 am 

State-of-the-Art: Eosinophils Shape the Immune Landscape to Promote Homeostasis 

Isabelle Arnold, Switzerland  

8:51 am – 9:11 am  

Cutting-Edge: Stromal Cell and B cell Dialogue Potentiates IL-33-Enriched Lymphoid Niches to Support Eosinophil Recruitment and Function During Type 2 Immunity 

Lalit Kumar Dubey, United Kingdom

9:12 am – 9:32 am 

Cutting-Edge: Bacterial Skin Infection Reprograms Eosinophils with Consequences for Allergic Lung Inflammation

Philipp Starkl, Austria

9:33 am – 9:48 am

Oral Abstract 

9:49 am – 10:04 am

Oral Abstract 

10:05 am – 10:20 am

Oral Abstract 

10:21 am – 10:26 am

Abstract Slam 

10:30 am – 11:15 am

Coffee Break & Poster Viewing

11:15 am – 12:45 pm

Session 7: Eosinophils and Tissue Repair

11:15 am – 11:35 am

State-of-the-Art: Role of Eosinophils in Acute Liver Injury and Repair 

Cynthia Ju, United States  

11:36 am – 11:56 am

Cutting-Edge: Eosinophils Preserve Bone Homeostasis by Inhibiting Excessive Osteoclast Formation and Activity Via Eosinophil Peroxidase

Aline Bozec, Germany

11:57 am – 12:12 pm

Oral Abstract 

12:13 pm – 12:28 pm

Oral Abstract 

12:29 pm – 12:34 pm

Abstract Slam 

12:35 pm – 12:40 pm

Abstract Slam 

12:41 pm – 12:46 pm

Abstract Slam 

12:45 pm – 3:00 pm

Break

3:00 pm – 4:30 pm

Session 8: Mast Cells and Basophils – Joint Session with EMBRN

3:00 pm – 3:10 pm 

Introduction

Francesca Levi-Schaffer, Israel   

3:11 pm – 3:31 pm 

Cutting-Edge: Inflammasome Involvement in Anaphylactic Mast Cell Degranulation  

Soman Abraham, United States  

3:32 pm – 3:52 pm 

Cutting Edge: Basophils and Allergic Skin Inflammation  

Raif Geha, United States  

3:53 pm – 4:08 pm

Oral Abstract 

4:09 pm – 4:24 pm

Oral Abstract 

4:25 pm – 4:30 pm

Abstract Slam 

4:45 pm – 5:30 pm

Gerald J. Gleich Award Lecture

7:00 pm – 10:00 pm

Awards Dinner

8:30 am – 10:00 am

Roundtable Discussions

8:30 am – 9:15 am 

Why are Human Eosinophil Knock-Outs so Healthy Given the Many Roles Played by Eosinophils in Murine Health? 

Moderators:  
Matthew Drake, United States 
Manali Mukherjee, Canada  

9:15 am – 10:00 am

Biomarkers: From Bench to Bedside (Local/Peripheral, Quantity vs. Quality, Normal Eosinophil Counts) 

Moderators:  
Paneez Khoury, United States  
Fei Lei Kuang, United States  

10:00 am – 10:30 am

Coffee Break

10:30 am – 11:30 am

Technology and Techniques Session

10:30 am – 10:50 am 

Single-cell Analysis of Eosinophils 

Kristina Handler, Switzerland

10:50 am – 11:10 am 

Updated Methods for Flow Cytometry, Including Mass Cytometry/Cytof  

Gabriella Wilson, United States

11:10 am – 11:30 am 

Quantitative Analysis of Eosinophil Location in Tissue Using 3D Imaging 

Alexandra Pincus, United States  

11:30 am – 12:00 pm

Lunch Break

Lunch Boxes Provided

12:00 pm – 2:00 pm

Pro/Con Debates

12:00 pm – 1:00 pm

Biologics Targeting T2 Responses are Better than those Targeting Eosinophils for the Treatment of Eosinophilic Asthma  

Pro: Michael Wechsler, United States

Con: Parameswaran Nair, Canada

1:00 pm – 2:00 pm 

What is the Key Factor in Determining Eosinophil Heterogeneity?

Environment:  Lisa Spencer, United States

Pre-Determined: Sergejs Berdnikovs, United States  

2:00 pm – 2:15 pm

Closing Remarks